PMID: 486087

 

    Legend: Sugar

Title : Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement

Abstract :
  1. The sequences of amino acid residues 38--51 of the A-chain , and residues 42--90 of the C-chain , of human subcomponent C1q are given
  2. These results, along with previously published sequence data [Reid (1974) Biochem.J
  3. 141, 189--203; Reid (1977) Biochem.J
  4. 161, 247--251; Reid & Thompson (1978) Biochem.J
  5. 173, 863--868] allow the presentation, and comparison with each other, of the complete amino acid sequences of the collagen-like regions found in the A-, B- and C-chains of human subcomponent C1q
  6. Each chain has the continuity of its collagen-like Gly-X-Y repeating triplet amino acid sequence broken
  7. The B- and C-chains have alanine residues at positions B-9 and C-36 where glycine might be expected
  8. The A-chain has a threonine residue at position A-39, which is located between two Gly-X-Y triplets