PMID: 19508227

 

    Legend: Gene, Sites

Title : Glycosylation of tetraspanin Tspan-1 at four distinct sites promotes its transition through the endoplasmic reticulum

Abstract :
  1. We showed that Tspan-1 , a tetraspanin overexpressed in many human cancers, harbours oligosaccharides at all four potential N-glycosylation sites
  2. Its most abundant form contained only mannose-rich sugar chains but two distinct glycosylation sites could also contain complex carbohydrates
  3. Glycosylation seemed to be required for correct folding and subsequent transition through the endoplasmic reticulum
Output (sent_index, trigger, protein, sugar, site):
  • 0. Glycosylation, , Tspan-1, -, sites
  • 2. contain, , -, complex carbohydrates, sites
  • 2. glycosylation, , -, -, sites
Output(Part-Of) (sent_index, protein, site):
*Output_Site_Fusion* (sent_index, protein, sugar, site):

 

 

Protein NCBI ID SENTENCE INDEX
Tspan-1 10103 0,1