Title : Interleukin-1
receptor antagonist activity of a human
interleukin-1 inhibitor
Abstract :
- Three interleukin-1 inhibitors have been purified to homogeneity from medium conditioned by human monocytes
- Partial sequence analysis and digestion with N-glycanase indicate that these are glycosylation forms of a single protein
- The protein binds to the interleukin-1 receptor but has no interleukin-1-like activity, even at very high concentrations, and is therefore a pure receptor antagonist
Output (sent_index, trigger,
protein,
sugar,
site):
Output(Part-Of) (sent_index,
protein,
site):
*Output_Site_Fusion* (sent_index,
protein,
sugar,
site):