Title : N-terminal amino acid
sequence of
sialoglycoprotein D (
glycophorin C ) from human erythrocyte membranes
Abstract :
- The amino acid sequence of the N-terminal tryptic glycopeptide from a minor human erythrocyte membrane sialoglycoprotein (component D or glycophorin C ) was determined by manual sequencing
- The glycosylation sites were identified by a new procedure for the detection of the glycosylated derivatives released by Edman degradation
- The fragment , comprising 47 residues, was found to contain an average of about 12 O-glycosidically linked oligosaccharides and one asparagine-linked carbohydrate chain
- An identical hexapeptide sequence occurring in two regions of the glycopeptide provides evidence that it has developed by an internal gene duplication during evolution
- In addition, a part of its structure shows a striking similarity to the sequence of a certain region of the MN and Ss erythrocyte membrane sialoglycoproteins ( glycophorins A and B ), suggesting that the molecules might be related
Output (sent_index, trigger,
protein,
sugar,
site):
- 0. sialoglycoprotein, , sialoglycoprotein D, -, -
- 1. glycopeptide, , sialoglycoprotein, -, glycopeptide
- 1. sialoglycoprotein, , sialoglycoprotein, -, -
- 2. glycosylation, , -, -, sites
- 3. asparagine-linked, , -, one asparagine-linked carbohydrate chain, asparagine
- 4. glycopeptide, , -, -, glycopeptide
- 5. sialoglycoproteins, , sialoglycoproteins, -, -
Output(Part-Of) (sent_index,
protein,
site):
- 0. sialoglycoprotein D, sequence
- 1. sialoglycoprotein, glycopeptide
- 1. sialoglycoprotein, sequence
- 5. sialoglycoproteins, region
*Output_Site_Fusion* (sent_index,
protein,
sugar,
site):