PMID: 7524900

 

    Legend: Gene, Sites

Title : Location and nature of carbohydrate groups in proform of human major basic protein isolated from pregnancy serum

Abstract :

1. From human pregnancy serum we have isolated the proform of eosinophil major basic protein ( proMBP ), which forms a complex with pregnancy-associated plasma protein-A ( PAPP-A ), PAPP-A / proMBP
2. It is shown that proMBP contains O-linked glycan bound to Ser-24, Thr-25 (fully substituted), and to Thr-23 and Thr-34 (partially substituted)
3. N-linked glycan is bound to Asn-86 and O-linked glycosaminoglycan is bound to Ser-62 (both fully substituted)
4. From the RP-HPLC elution profile and mass spectra of tryptic peptides it is found that proMBP is extremely heterogeneous with respect to glycosylation

Output (sent_index, trigger, protein, sugar, site):

• 2. contains, , proMBP, O-linked glycan, -

Output(Part-Of) (sent_index, protein, site):

*Output_Site_Fusion* (sent_index, protein, sugar, site):

 

Protein	NCBI ID	SENTENCE INDEX
eosinophil major basic protein	5553	1
proMBP	5553	1,2,4