Title : Central to this study is the explorative, nontargeted analysis of O-glycosylated blood plasma
glycoproteins
Abstract :
- To this end a glycoproteomics approach was applied, that includes the identification of the peptide moiety as well as a characterization and localization of the O-glycosylation sites with the characterization of the corresponding O-glycans
- HILIC enriched glycopeptides derived from a broad-specific proteolytic digest of human blood plasma proteins were analyzed by reversed-phase liquid chromatography combined with multistage mass spectrometry (CID- MS2 /-MS3, ETD- MS2 fragmentation )
Output (sent_index, trigger,
protein,
sugar,
site):
- 0. O-glycosylated, , glycoproteins, -, -
- 0. glycoproteins, , glycoproteins, -, -
- 1. O-glycosylation, , -, -, sites
- 2. glycopeptides, , -, -, glycopeptides
Output(Part-Of) (sent_index,
protein,
site):
*Output_Site_Fusion* (sent_index,
protein,
sugar,
site):