Title : Glycan heterogeneity by
glycoprotein
Abstract :
- A scatter plot showing the number of glycans identified per glycoprotein vs. the number of glycosites identified for that protein summarizes a degree of glycosylation heterogeneity at the protein level
- An y = x line is shown in gray to provide an eye guide for proteins that had a particularly high number of glycans relative to the number of glycosites identified, some of which are highlighted
- Boxes for highlighted proteins display gene name (GN), UniProt accession number, number of glycosites/glycans identified, the cellular location assigned to this protein, and a common name for the protein
- Additionally, they provide a bar chart that displays the percentage of the total number of identified glycans (i.e., the x-axis) that can be classified as paucimannose, high mannose , fucosylated, or sialylated (NeuAc)
- Note, if a paucimannose or sialylated glycan was fucosylated, it was also counted as fucosylated for this calculation
- Gene names of other interesting proteins with a high glycan-to-glycosite ratio are also provide
Output (sent_index, trigger,
protein,
sugar,
site):
- 0. glycoprotein, , glycoprotein, -, -
- 1. glycoprotein, , glycoprotein, -, -
- 1. glycosites, , -, -, glycosites
- 2. glycosites, , -, -, glycosites
- 6. glycan-to-glycosite, , -, -, glycan-to-glycosite
Output(Part-Of) (sent_index,
protein,
site):
*Output_Site_Fusion* (sent_index,
protein,
sugar,
site):